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2C70

Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins

Summary for 2C70
Entry DOI10.2210/pdb2c70/pdb
Related1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C72 2C73 2C75 2C76
DescriptorAMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, P-NITRO-BENZYLAMINE, ... (4 entities in total)
Functional Keywordsoxidoreductase, enantioselectivity, fad, flavin, flavoprotein, human monoamine oxidase, inhibitor binding, mitochondrion, rasagiline, transmembrane, parkinson
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P27338
Total number of polymer chains2
Total formula weight119550.86
Authors
Li, M.,Binda, C.,Mattevi, A.,Edmondson, D.E. (deposition date: 2005-11-17, release date: 2006-04-19, Last modification date: 2023-12-13)
Primary citationLi, M.,Binda, C.,Mattevi, A.,Edmondson, D.E.
Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Biochemistry, 45:4775-, 2006
Cited by
PubMed: 16605246
DOI: 10.1021/BI051847G
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.06 Å)
Structure validation

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