2C6W
PENICILLIN-BINDING PROTEIN 1A (PBP-1A) FROM STREPTOCOCCUS PNEUMONIAE
Summary for 2C6W
| Entry DOI | 10.2210/pdb2c6w/pdb |
| Related | 2C5W |
| Descriptor | PENICILLIN-BINDING PROTEIN 1A, ZINC ION, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | peptidoglycan synthesis, cell wall, penicillin-binding, antibiotic resistance, cell shape, multifunctional enzyme |
| Biological source | STREPTOCOCCUS PNEUMONIAE More |
| Cellular location | Secreted: Q8DR59 Q8DR59 |
| Total number of polymer chains | 2 |
| Total formula weight | 45241.56 |
| Authors | Contreras-Martel, C.,Job, V.,Di Guilmi, A.-M.,Vernet, T.,Dideberg, O.,Dessen, A. (deposition date: 2005-11-14, release date: 2005-12-07, Last modification date: 2023-12-13) |
| Primary citation | Contreras-Martel, C.,Job, V.,Di Guilmi, A.-M.,Vernet, T.,Dideberg, O.,Dessen, A. Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae. J.Mol.Biol., 355:684-, 2006 Cited by PubMed: 16316661DOI: 10.1016/J.JMB.2005.10.030 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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