2C4F

crystal structure of factor VII.stf complexed with pd0297121

Summary for 2C4F

Entry DOI	10.2210/pdb2c4f/pdb
Related	1AHW 1BF9 1BOY 1CVW 1DAN 1DVA 1F7E 1F7M 1FAK 1FF7 1FFM 1J9C 1JBU 1JPS 1KLI 1KLJ 1NL8 1O5D 1QFK 1TFH 1UJ3 1W0Y 1W2K 1W7X 1W8B 1WQV 1YGC 1Z6J 2BZ6 2HFT
Descriptor	COAGULATION FACTOR VII PRECURSOR, TISSUE FACTOR PRECURSOR, CALCIUM ION, ... (10 entities in total)
Functional Keywords	blood coagulation, serine protease, egf, egf-like domain, gla, receptor enzyme, glycoprotein, hydrolase, protease, hydroxylation, lipoprotein, palmitate, transmembrane
Biological source	HOMO SAPIENS More
Total number of polymer chains	4
Total formula weight	67883.25
Authors	Kohrt, J.T.,Zhang, E. (deposition date: 2005-10-18, release date: 2006-10-18, Last modification date: 2020-07-29)
Primary citation	Kohrt, J.T.,Filipski, K.J.,Cody, W.L.,Cai, C.,Dudley, D.A.,Huis, C.A.V.,Willardsen, J.A.,Narasimhan, L.S.,Zhang, E.,Rapundalo, S.T.,Saiya-Cork, K.,Leadley, R.J.,Edmunds, J.J. The Discovery of Fluoropyridine-Based Inhibitors of the Factor Viia/Tf Complex--Part 2 Bioorg.Med.Chem.Lett., 16:1060-, 2006 Cited by PubMed: 16289811 DOI: 10.1016/J.BMCL.2005.10.076 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation