2C39

RNase PH core of the archaeal exosome in complex with ADP

Summary for 2C39

Entry DOI	10.2210/pdb2c39/pdb
Related	2BR2 2C37 2C38
Descriptor	PROBABLE EXOSOME COMPLEX EXONUCLEASE 2, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	exosome, rnase ph, rrp41, rrp42, phosphorolytic, exoribonuclease, rna degradation, archaeal, hydrolase, exonuclease, nuclease
Biological source	SULFOLOBUS SOLFATARICUS More
Cellular location	Cytoplasm (Potential): Q9UXC0 Q9UXC2
Total number of polymer chains	24
Total formula weight	699213.14
Authors	Lorentzen, E.,Conti, E. (deposition date: 2005-10-05, release date: 2005-11-23, Last modification date: 2023-12-13)
Primary citation	Lorentzen, E.,Conti, E. Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core. Mol.Cell, 20:473-, 2005 Cited by PubMed: 16285928 DOI: 10.1016/J.MOLCEL.2005.10.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation