2C2E

Efficient and High Fidelity Incorporation of dCTP Opposite 7,8- Dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA Polymerase Dpo4

Summary for 2C2E

• Entry DOI: 10.2210/pdb2c2e/pdb
• Related: 1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2AGO 2AGP 2AGQ 2BQ3 2BQR 2BQU 2BR0 2C22 2C28 2C2D 2C2R
• Descriptor: DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*C)-3', 5'-D(*TP*CP*AP*C 8OGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
• Functional Keywords: polymerase, p2 dna polymerase iv, 7, 8-dihydro-8-oxodeoxyguanosine, translesion dna polymerase, nucleotidyltransferase, transferase, dna damage, dna repair, dna replication, dna- binding, dna-directed dna polymerase, magnesium, calcium, metal-binding, mutator protein
• Biological source: SULFOLOBUS SOLFATARICUS
• Cellular location: Cytoplasm (Probable): Q97W02
• Total number of polymer chains: 3
• Total formula weight: 51448.48

Authors

Irimia, A.,Loukachevitch, L.V.,Egli, M. (deposition date: 2005-09-27, release date: 2005-11-29, Last modification date: 2023-12-13)

• Primary citation: Zang, H.,Irimia, A.,Choi, J.-Y.,Angel, K.C.,Loukachevitch, L.V.,Egli, M.,P Guengerich, F.; Efficient and High Fidelity Incorporation of Dctp Opposite 7,8-Dihydro-8-Oxodeoxyguanosine by Sulfolobus Solfataricus DNA Polymerase Dpo4; J.Biol.Chem., 281:2358-, 2006; PubMed: 16306039; DOI: 10.1074/JBC.M510889200

Experimental method

X-RAY DIFFRACTION (2.61 Å)