2C22

Efficient and High Fidelity Incorporation of dCTP Opposite 7,8- Dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA Polymerase Dpo4

2C22 の概要

• エントリーDOI: 10.2210/pdb2c22/pdb
• 関連するPDBエントリー: 1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2AGO 2AGP 2AGQ 2BQ3 2BQR 2BQU 2BR0 2C28 2C2D 2C2E 2C2R
• 分子名称: DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*C)-3', 5'-D(TP*CP*AP*C 8OGP*GP*AP*AP*TP*CP*CP*TP *TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
• 機能のキーワード: polymerase, p2 dna polymerase iv, 7, 8-dihydro-8-oxodeoxyguanosine, translesion dna polymerase, nucleotidyltransferase, transferase, dna damage, dna repair, dna replication, dna- binding, dna-directed dna polymerase, magnesium, metal - binding, mutator protein
• 由来する生物種: SULFOLOBUS SOLFATARICUS
• 細胞内の位置: Cytoplasm (Probable): Q97W02
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 51199.32

構造登録者

Irimia, A.,Loukachevitch, L.V.,Egli, M. (登録日: 2005-09-26, 公開日: 2005-11-29, 最終更新日: 2023-12-13)

• 主引用文献: Zang, H.,Irimia, A.,Choi, J.-Y.,Angel, K.C.,Loukachevitch, L.V.,Egli, M.,Guengerich, F.P.; Efficient and High Fidelity Incorporation of Dctp Opposite 7,8-Dihydro-8-Oxodeoxyguanosine by Sulfolobus Solfataricus DNA Polymerase Dpo4; J.Biol.Chem., 281:2358-, 2006; PubMed: 16306039; DOI: 10.1074/JBC.M510889200

実験手法

X-RAY DIFFRACTION (2.56 Å)