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2BZM

Solution structure of the primary host recognition region of complement factor H

Summary for 2BZM
Entry DOI10.2210/pdb2bzm/pdb
Related1FHC 1HAQ 1HCC 1HFH 1HFI 1KOV
DescriptorCOMPLEMENT FACTOR H (1 entity in total)
Functional Keywordsimmune system, factor h, complement, hus, heparin, polyanions, immune response, innate immunity, complement alternate pathway
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted: P08603
Total number of polymer chains1
Total formula weight14773.79
Authors
Herbert, A.P.,Uhrin, D.,Lyon, M.,Pangburn, M.K.,Barlow, P.N. (deposition date: 2005-08-18, release date: 2006-03-22, Last modification date: 2011-07-13)
Primary citationHerbert, A.P.,Uhrin, D.,Lyon, M.,Pangburn, M.K.,Barlow, P.N.
Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure.
J.Biol.Chem., 281:16512-, 2006
Cited by
PubMed: 16533809
DOI: 10.1074/JBC.M513611200
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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