2BVE

STRUCTURE OF THE N-TERMINAL OF SIALOADHESIN IN COMPLEX WITH 2-PHENYL-PROP5AC

Summary for 2BVE

Related1OD7 1OD9 1ODA 1QFO 1QFP 1URL
DescriptorSIALOADHESIN
Functional Keywordsimmune system, immunoglobulin, lectin, superfamily, carbohydrate binding, siglec, inhibitor design, cell adhesion
Biological sourceMUS MUSCULUS (MOUSE)
Cellular locationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted Q62230
Total number of polymer chains2
Total molecular weight27465.27
Authors
Zaccai, N.R.,May, A.P.,Robinson, R.C.,Burtnick, L.D.,Crocker, P.,Brossmer, R.,Kelm, S.,Jones, E.Y. (deposition date: 2005-06-27, release date: 2006-07-19, modification date: 2009-06-02)
Primary citation
Zaccai, N.R.,May, A.P.,Robinson, R.C.,Burtnick, L.D.,Crocker, P.,Brossmer, R.,Kelm, S.,Jones, E.Y.
Crystallographic and in Silico Analysis of the Sialoside-Binding Characteristics of the Siglec Sialoadhesin.
J.Mol.Biol., 365:1469-1479, 2007
PubMed: 17137591
DOI: 10.1016/j.jmb.2006.10.084
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers130.4%6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2bve
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Molmil generated image of 2bve
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Molmil generated image of 2bve
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More Biological unit images

Molmil generated image of 2bve
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Molmil generated image of 2bve
rotated about x axis by 90°
Molmil generated image of 2bve
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2bve.pdb1.gz [22.45 KB])
Coordinate files for Biological unit (2bve.pdb2.gz [22.74 KB])
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