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2BNR

Structural and kinetic basis for heightened immunogenicity of T cell vaccines

Summary for 2BNR
Entry DOI10.2210/pdb2bnr/pdb
Related1A1M 1A1N 1A1O 1A6Z 1A9B 1A9E 1AGB 1AGC 1AGD 1AGE 1AGF 1AKJ 1AO7 1B0G 1B0R 1BD2 1CE6 1DE4 1DUY 1DUZ 1E27 1E28 1EFX 1EXU 1FYT 1GZP 1GZQ 1HHG 1HHH 1HHI 1HHJ 1HHK 1HLA 1HSA 1HSB 1I1F 1I1Y 1I4F 1I7R 1I7T 1I7U 1IM3 1IM9 1JF1 1JGE 1JHT 1JNJ 1K5N 1KGC 1KPR 1KTL 1LDS 1OF2 1QLF 1QQD 1QR1 1QRN 1QSE 1QSF 1TMC 2BNQ 2CLR 2HLA 3HLA
DescriptorHLA CLASS I HISTOCOMPATIBILITY ANTIGEN, BETA-2-MICROGLOBULIN, SYNTHETIC PEPTIDE, ... (6 entities in total)
Functional Keywordsimmune system/receptor, immune system-receptor-complex, tcr, mhc, immunodominance, flu, complex, transmembrane, glycoprotein, polymorphism, t-cell, receptor, superagonist peptide t-cell vaccines, immune system-receptor complex
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted : P61769
Membrane ; Single-pass membrane protein : 2BNR
Total number of polymer chains5
Total formula weight94102.49
Authors
Primary citationChen, J.-L.,Stewart-Jones, G.,Bossi, G.,Lissin, N.M.,Wooldridge, L.,Choi, E.M.L.,Held, G.,Dunbar, P.R.,Esnouf, R.M.,Sami, M.,Boultier, J.M.,Rizkallah, P.,Renner, C.,Sewell, A.,Van Der Merwe, P.A.,Jackobsen, B.K.,Griffiths, G.,Jones, E.Y.,Cerundolo, V.
Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201:1243-, 2005
Cited by
PubMed: 15837811
DOI: 10.1084/JEM.20042323
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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