2BN4

A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of electron transfer by diflavin reductase

Summary for 2BN4

• Entry DOI: 10.2210/pdb2bn4/pdb
• Related: 2BF4
• Descriptor: NADPH CYTOCHROME P450 REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: oxidoreductase, diflavin reductase, cpr, electron transfer, fmn-binding, fad, flavoprotein, nadph, oxidoreductase.
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
• Total number of polymer chains: 2
• Total formula weight: 155656.69

Authors

Podust, L.M.,Lepesheva, G.I.,Kim, Y.,Yermalitskaya, L.V.,Yermalitsky, V.N.,Lamb, D.C.,Kelly, S.L.,Waterman, M.R. (deposition date: 2005-03-18, release date: 2006-01-17, Last modification date: 2023-12-13)

• Primary citation: Lamb, D.C.,Kim, Y.,Yermalitskaya, L.V.,Yermalitsky, V.N.,Lepesheva, G.I.,Kelly, S.L.,Waterman, M.R.,Podust, L.M.; A Second Fmn-Binding Site in Yeast Nadph-Cytochrome P450 Reductase Suggests a Mechanism of Electron Transfer by Diflavin Reductases.; Structure, 14:51-, 2006; PubMed: 16407065; DOI: 10.1016/J.STR.2005.09.015

Experimental method

X-RAY DIFFRACTION (2.91 Å)