2BIJ
Crystal structure of the human protein tyrosine phosphatase PTPN5 (STEP, striatum enriched enriched Phosphatase)
Summary for 2BIJ
Entry DOI | 10.2210/pdb2bij/pdb |
Descriptor | TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5, SULFATE ION (3 entities in total) |
Functional Keywords | ptpn5, step, phosphatase, hydrolase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 35300.91 |
Authors | Barr, A.J.,Debreczeni, J.E.,Eswaran, J.,Smee, C.,Burgess, N.,Gileadi, O.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Knapp, S.,von Delft, F. (deposition date: 2005-01-21, release date: 2005-03-17, Last modification date: 2023-12-13) |
Primary citation | Eswaran, J.,von Kries, J.P.,Marsden, B.,Longman, E.,Debreczeni, J.E.,Ugochukwu, E.,Turnbull, A.,Lee, W.H.,Knapp, S.,Barr, A.J. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem. J., 395:483-491, 2006 Cited by PubMed: 16441242DOI: 10.1042/BJ20051931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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