2BEC

Crystal structure of CHP2 in complex with its binding region in NHE1 and insights into the mechanism of pH regulation

Summary for 2BEC

Entry DOI	10.2210/pdb2bec/pdb
Descriptor	Calcineurin B homologous protein 2, Sodium/hydrogen exchanger 1, YTTRIUM (III) ION (3 entities in total)
Functional Keywords	calcineurin-homologous protein, calcium-binding protein, nhe1 regulating protein, metal binding protein-transport protein complex, metal binding protein/transport protein
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Multi-pass membrane protein: P19634
Total number of polymer chains	2
Total formula weight	28509.78
Authors	Ben Ammar, Y.,Takeda, S.,Hisamitsu, T.,Mori, H.,Wakabayashi, S. (deposition date: 2005-10-24, release date: 2006-06-27, Last modification date: 2024-03-13)
Primary citation	Ben Ammar, Y.,Takeda, S.,Hisamitsu, T.,Mori, H.,Wakabayashi, S. Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation Embo J., 25:2315-2325, 2006 Cited by PubMed: 16710297 DOI: 10.1038/sj.emboj.7601145 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation