2B5T

2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules

Summary for 2B5T

Entry DOI	10.2210/pdb2b5t/pdb
Related	1NQ9 1T1F 1TB6
Descriptor	Thrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... (11 entities in total)
Functional Keywords	blood coagulation, blood clotting
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	128613.87
Authors	Johnson, D.J.,Li, W.,Luis, S.A.,Carrell, R.W.,Huntington, J.A. (deposition date: 2005-09-29, release date: 2006-09-19, Last modification date: 2023-08-23)
Primary citation	Johnson, D.J.,Langdown, J.,Li, W.,Luis, S.A.,Baglin, T.P.,Huntington, J.A. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation. J.Biol.Chem., 281:35478-35486, 2006 Cited by PubMed: 16973611 DOI: 10.1074/jbc.M607204200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation