2B50

Human Nuclear Receptor-Ligand Complex 2

Summary for 2B50

• Entry DOI: 10.2210/pdb2b50/pdb
• Related: 2AWH
• Descriptor: Peroxisome proliferator activated receptor delta, CALCIUM ION, heptyl beta-D-glucopyranoside, ... (5 entities in total)
• Functional Keywords: nuclear receptor, protein-ligand complex, ppar, gene regulation
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 63261.88

Authors

Fyffe, S.A.,Alphey, M.S.,Buetow, L.,Smith, T.K.,Ferguson, M.A.J.,Sorensen, M.D.,Bjorkling, F.,Hunter, W.N. (deposition date: 2005-09-27, release date: 2006-02-14, Last modification date: 2024-03-13)

• Primary citation: Fyffe, S.A.,Alphey, M.S.,Buetow, L.,Smith, T.K.,Ferguson, M.A.J.,Sorensen, M.D.,Bjorkling, F.,Hunter, W.N.; Recombinant Human PPAR-beta/delta Ligand-binding Domain is Locked in an Activated Conformation by Endogenous Fatty Acids; J.Mol.Biol., 356:1005-1013, 2006; PubMed: 16405912; DOI: 10.1016/j.jmb.2005.12.047

Experimental method

X-RAY DIFFRACTION (2 Å)