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2AWG

Structure of the PPIase domain of the Human FK506-binding protein 8

Summary for 2AWG
Entry DOI10.2210/pdb2awg/pdb
Descriptor38 kDa FK-506 binding protein (2 entities in total)
Functional Keywordsfkbp-type, ppiase, bcl-2 inhibitor, shh signalling antagonist, structural genomics consortium, sgc, signaling protein inhibitor
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion membrane; Single-pass membrane protein; Cytoplasmic side (By similarity): Q14318
Total number of polymer chains1
Total formula weight12638.40
Authors
Primary citationWalker, J.R.,Davis, T.,Newman, E.M.,Finerty, P.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S.
Structure of the human FK-506 binding protein 8
To be Published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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PDB entries from 2024-03-27

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