2ARR
Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagmggvmtgr-oh
Summary for 2ARR
| Entry DOI | 10.2210/pdb2arr/pdb |
| Related | 1JRR 2ARQ |
| Descriptor | Plasminogen activator inhibitor-2, 14-mer from Plasminogen activator inhibitor-2 (3 entities in total) |
| Functional Keywords | serpin, peptide binding, inhibitor, hydrolase inhibitor-peptide complex, hydrolase inhibitor/peptide |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 44322.45 |
| Authors | Di Giusto, D.A.,Sutherland, A.P.,Jankova, L.,Harrop, S.J.,Curmi, P.M.,King, G.C. (deposition date: 2005-08-21, release date: 2006-07-11, Last modification date: 2023-10-25) |
| Primary citation | Di Giusto, D.A.,Sutherland, A.P.,Jankova, L.,Harrop, S.J.,Curmi, P.M.,King, G.C. Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities J.Mol.Biol., 353:1069-1080, 2005 Cited by PubMed: 16214170DOI: 10.1016/j.jmb.2005.09.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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