2ARJ

CD8alpha-alpha in complex with YTS 105.18 Fab

Summary for 2ARJ

Entry DOI	10.2210/pdb2arj/pdb
Related	1AKJ 1BQH 1CD8 1NEZ 1Q69
Descriptor	YTS 105.18 antigen binding region Light chain, YTS 105.18 antigen binding region Heavy chain, T-cell surface glycoprotein CD8 alpha chain, ... (4 entities in total)
Functional Keywords	protein-protein complex, antibody fab, immune system, immunoglobulin domain
Biological source	Mus musculus (house mouse) More
Cellular location	Membrane; Single-pass type I membrane protein: P01731
Total number of polymer chains	6
Total formula weight	120683.41
Authors	Shore, D.A.,Teyton, L.,Dwek, R.A.,Rudd, P.M.,Wilson, I.A. (deposition date: 2005-08-19, release date: 2006-05-30, Last modification date: 2023-08-23)
Primary citation	Shore, D.A.,Teyton, L.,Dwek, R.A.,Rudd, P.M.,Wilson, I.A. Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution. J.Mol.Biol., 358:347-354, 2006 Cited by PubMed: 16530222 DOI: 10.1016/j.jmb.2006.02.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.88 Å)

Structure validation