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2ANT

THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE

Summary for 2ANT
Entry DOI10.2210/pdb2ant/pdb
DescriptorANTITHROMBIN, 2-acetamido-2-deoxy-beta-D-allopyranose (3 entities in total)
Functional Keywordsserpin, heparin, inhibitor
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space: P01008
Total number of polymer chains2
Total formula weight98644.45
Authors
Skinner, R.,Abrahams, J.-P.,Whisstock, J.C.,Lesk, A.M.,Carrell, R.W.,Wardell, M.R. (deposition date: 1997-01-28, release date: 1997-06-16, Last modification date: 2023-08-09)
Primary citationSkinner, R.,Abrahams, J.P.,Whisstock, J.C.,Lesk, A.M.,Carrell, R.W.,Wardell, M.R.
The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site.
J.Mol.Biol., 266:601-609, 1997
Cited by
PubMed: 9067613
DOI: 10.1006/jmbi.1996.0798
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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