2AJY

Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester and benzoic acid

Summary for 2AJY

• Entry DOI: 10.2210/pdb2ajy/pdb
• Related: 2AJS 2AJU 2AJV 2AJX 2AJZ 2AK1
• Descriptor: Antibody 7A1 Fab', ZINC ION, 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER, ... (6 entities in total)
• Functional Keywords: catalytic antibody, fab, ecgonine methyl ester, benzoic acid, hydrolytic, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 48573.81

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2005-08-02, release date: 2006-02-14, Last modification date: 2023-08-23)

• Primary citation: Zhu, X.,Dickerson, T.J.,Rogers, C.J.,Kaufmann, G.F.,Mee, J.M.,McKenzie, K.M.,Janda, K.D.,Wilson, I.A.; Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.; Structure, 14:205-216, 2006; PubMed: 16472740; DOI: 10.1016/j.str.2005.10.014

Experimental method

X-RAY DIFFRACTION (2.1 Å)