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2AG2

Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine

Summary for 2AG2
Entry DOI10.2210/pdb2ag2/pdb
Related1G13 1PU5 1PUB 1TJJ
DescriptorGanglioside GM2 activator, CHLORIDE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (10 entities in total)
Functional Keywordsphospholipid-protein complex, lipid acyl chain stacking, packaging, lipid binding protein
Biological sourceHomo sapiens (human)
Cellular locationLysosome: P17900
Total number of polymer chains3
Total formula weight58503.79
Authors
Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F. (deposition date: 2005-07-26, release date: 2005-10-25, Last modification date: 2023-08-23)
Primary citationWright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F.
Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44:13510-13521, 2005
Cited by
PubMed: 16216074
DOI: 10.1021/bi050668w
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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