2AA6

Mineralocorticoid Receptor S810L Mutant with Bound Progesterone

Summary for 2AA6

Entry DOI	10.2210/pdb2aa6/pdb
Related	2AA2 2AA5 2AA7 2AAR 2AAX 2AB2
Descriptor	Mineralocorticoid receptor, PROGESTERONE (3 entities in total)
Functional Keywords	mineralocorticoid receptor, mr, nuclear receptor, steroid receptor, progesterone, hypertension, transcription
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P08235
Total number of polymer chains	2
Total formula weight	63902.12
Authors	Bledsoe, R.K.,Madauss, K.P.,Holt, J.A.,Apolito, C.J.,Lambert, M.H.,Pearce, K.H.,Stanley, T.B.,Stewart, E.L.,Trump, R.P.,Willson, T.M.,Williams, S.P. (deposition date: 2005-07-13, release date: 2005-07-26, Last modification date: 2024-02-14)
Primary citation	Bledsoe, R.K.,Madauss, K.P.,Holt, J.A.,Apolito, C.J.,Lambert, M.H.,Pearce, K.H.,Stanley, T.B.,Stewart, E.L.,Trump, R.P.,Willson, T.M.,Williams, S.P. A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor J.Biol.Chem., 280:31283-31293, 2005 Cited by PubMed: 15967794 DOI: 10.1074/jbc.M504098200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation