2A24

HADDOCK Structure of HIF-2a/ARNT PAS-B Heterodimer

Summary for 2A24

• Entry DOI: 10.2210/pdb2a24/pdb
• NMR Information: BMRB: 6597
• Descriptor: Endothelial PAS domain protein 1, Aryl hydrocarbon receptor nuclear translocator (2 entities in total)
• Functional Keywords: arnt, hif, hypoxia, transcription, pas
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus (Potential): Q99814; Nucleus: P27540
• Total number of polymer chains: 2
• Total formula weight: 25311.76

Authors

Card, P.B.,Erbel, P.J.,Gardner, K.H. (deposition date: 2005-06-21, release date: 2006-01-17, Last modification date: 2022-03-09)

• Primary citation: Card, P.B.,Erbel, P.J.,Gardner, K.H.; Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.; J.Mol.Biol., 353:664-677, 2005; PubMed: 16181639; DOI: 10.1016/j.jmb.2005.08.043

Experimental method

SOLUTION NMR