2A0Q

Structure of thrombin in 400 mM potassium chloride

Summary for 2A0Q

Entry DOI	10.2210/pdb2a0q/pdb
Descriptor	Thrombin, light chain, Thrombin, heavy chain, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywords	serine protease, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	66386.65
Authors	Papaconstantinou, M.,Carrell, C.J.,Pineda, A.O.,Bobofchak, K.M.,Mathews, F.S.,Flordellis, C.S.,Maragoudakis, M.E.,Tsopanoglou, N.E.,di Cera, E. (deposition date: 2005-06-16, release date: 2005-07-12, Last modification date: 2021-10-20)
Primary citation	Papaconstantinou, M.E.,Carrell, C.J.,Pineda, A.O.,Bobofchak, K.M.,Mathews, F.S.,Flordellis, C.S.,Maragoudakis, M.E.,Tsopanoglou, N.E.,Di Cera, E. Thrombin Functions through Its RGD Sequence in a Non-canonical Conformation. J.Biol.Chem., 280:29393-29396, 2005 Cited by PubMed: 15998637 DOI: 10.1074/jbc.C500248200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation