2DHH
Crystal structure of a multidrug transporter reveal a functionally rotating mechanism
Summary for 2DHH
| Entry DOI | 10.2210/pdb2dhh/pdb |
| Related | 2DR6 2DRD |
| Descriptor | ACRB (2 entities in total) |
| Functional Keywords | membrane transporter, membrane protein, multidrug efflux, drug resistance, transporter, exporter, antiporter |
| Biological source | Escherichia coli |
| Cellular location | Cell inner membrane; Multi-pass membrane protein: P31224 |
| Total number of polymer chains | 3 |
| Total formula weight | 342653.23 |
| Authors | Murakami, S.,Nakashima, R.,Yamashita, E.,Matsumoto, T. (deposition date: 2006-03-23, release date: 2006-08-22, Last modification date: 2024-03-13) |
| Primary citation | Murakami, S.,Nakashima, R.,Yamashita, E.,Matsumoto, T.,Yamaguchi, A. Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Nature, 443:173-179, 2006 Cited by PubMed: 16915237DOI: 10.1038/nature05076 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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