278D

SUBSTITUTIONS AT C2' OF DAUNOSAMINE IN THE ANTICANCER DAUNORUBICIN ALTER ITS DNA-BINDING SEQUENCE SPECIFICITY

Summary for 278D

• Entry DOI: 10.2210/pdb278d/pdb
• Descriptor: DNA (5'-D(*CP*GP*(G49)P*CP*CP*G)-3', 2'-BROMO-4'-EPIDAUNORUBICIN (3 entities in total)
• Functional Keywords: right handed dna, double helix, complexed with drug, modified, dna
• Total number of polymer chains: 1
• Total formula weight: 2430.65

Authors

Gao, Y.-G.,Priebe, W.,Wang, A.H.-J. (deposition date: 1996-07-22, release date: 1996-09-16, Last modification date: 2024-02-14)

• Primary citation: Gao, Y.G.,Priebe, W.,Wang, A.H.; Substitutions at C2' of daunosamine in the anticancer drug daunorubicin alter its DNA-binding sequence specificity.; Eur.J.Biochem., 240:331-335, 1996; PubMed: 8841395; DOI: 10.1111/j.1432-1033.1996.0331h.x

Experimental method

X-RAY DIFFRACTION (1.8 Å)