235D

CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK

Summary for 235D

• Entry DOI: 10.2210/pdb235d/pdb
• Descriptor: DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), 3'-DESAMINO-3'-(2-METHOXY-4-MORPHOLINYL)-DOXORUBICIN (3 entities in total)
• Functional Keywords: right handed dna, double helix, complexed with drug, dna
• Total number of polymer chains: 1
• Total formula weight: 2452.85

Authors

Gao, Y.-G.,Wang, A.H.-J. (deposition date: 1995-06-22, release date: 1996-01-31, Last modification date: 2024-02-14)

• Primary citation: Gao, Y.G.,Wang, A.H.; Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink.; J.Biomol.Struct.Dyn., 13:103-117, 1995; PubMed: 8527023

Experimental method

X-RAY DIFFRACTION (1.8 Å)