1ZZQ

Rat nNOS D597N mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide bound

Summary for 1ZZQ

• Entry DOI: 10.2210/pdb1zzq/pdb
• Related: 1P6J
• Descriptor: Nitric-oxide synthase, brain, ACETATE ION, ZINC ION, ... (8 entities in total)
• Functional Keywords: oxydoreductase enzyme-inhibitor complex, oxidoreductase
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Cell membrane, sarcolemma; Peripheral membrane protein (By similarity): P29476
• Total number of polymer chains: 2
• Total formula weight: 100146.56

Authors

Li, H.,Flinspach, M.L.,Igarashi, J.,Jamal, J.,Yang, W.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2005-06-14, release date: 2005-12-06, Last modification date: 2024-02-14)

• Primary citation: Li, H.,Flinspach, M.L.,Igarashi, J.,Jamal, J.,Yang, W.,Litzinger, E.A.,Huang, H.,Erdal, E.P.,Silverman, R.B.,Poulos, T.L.; Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.; Biochemistry, 44:15222-15229, 2005; PubMed: 16285725; DOI: 10.1021/bi0513610

Experimental method

X-RAY DIFFRACTION (1.9 Å)