1ZVD

Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain

Summary for 1ZVD

Entry DOI	10.2210/pdb1zvd/pdb
Descriptor	Smad ubiquitination regulatory factor 2, SODIUM ION, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	ubiquitin ligasecatalytic mechanism, x-ray crystal structure, tgfbeta, ligase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q9HAU4
Total number of polymer chains	1
Total formula weight	44953.13
Authors	Ogunjimi, A.A.,Briant, D.J.,Pece-Barbara, N.,Le Roy, C.,Di Guglielmo, G.M.,Kavsak, P.,Rasmussen, R.K.,Seet, B.T.,Sicheri, F.,Wrana, J.L. (deposition date: 2005-06-01, release date: 2005-08-09, Last modification date: 2011-09-28)
Primary citation	Ogunjimi, A.A.,Briant, D.J.,Pece-Barbara, N.,Le Roy, C.,Di Guglielmo, G.M.,Kavsak, P.,Rasmussen, R.K.,Seet, B.T.,Sicheri, F.,Wrana, J.L. Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain. Mol.Cell, 19:297-308, 2005 Cited by PubMed: 16061177 DOI: 10.1016/j.molcel.2005.06.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation