1ZRZ

Crystal Structure of the Catalytic Domain of Atypical Protein Kinase C-iota

Summary for 1ZRZ

• Entry DOI: 10.2210/pdb1zrz/pdb
• Related: 1XJD
• Descriptor: Protein kinase C, iota, 3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE (3 entities in total)
• Functional Keywords: protein-inhibitor complex, structural genomics, structural proteomics in europe, spine, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P41743
• Total number of polymer chains: 1
• Total formula weight: 42408.73

Authors

Messerschmidt, A.,Macieira, S.,Velarde, M.,Baedeker, M.,Benda, C.,Jestel, A.,Brandstetter, H.,Neuefeind, T.,Blaesse, M.,Structural Proteomics in Europe (SPINE) (deposition date: 2005-05-23, release date: 2005-09-13, Last modification date: 2023-08-23)

• Primary citation: Messerschmidt, A.,Macieira, S.,Velarde, M.,Baedeker, M.,Benda, C.,Jestel, A.,Brandstetter, H.,Neuefeind, T.,Blaesse, M.; Crystal Structure of the Catalytic Domain of Human Atypical Protein Kinase C-iota Reveals Interaction Mode of Phosphorylation Site in Turn Motif; J.Mol.Biol., 352:918-931, 2005; PubMed: 16125198; DOI: 10.1016/j.jmb.2005.07.060

Experimental method

X-RAY DIFFRACTION (3 Å)