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1ZR0

Crystal Structure of Kunitz Domain 1 of Tissue Factor Pathway Inhibitor-2 with Bovine Trypsin

Summary for 1ZR0
Entry DOI10.2210/pdb1zr0/pdb
Related1TAW
DescriptorCationic trypsin, Tissue factor pathway inhibitor 2, CALCIUM ION, ... (4 entities in total)
Functional Keywordsserine protease; complex of serine protease-inhibitor; kunitz type inhibitor, hydrolase-blood clotting complex, hydrolase/blood clotting
Biological sourceHomo sapiens (human)
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Cellular locationSecreted, extracellular space: P00760
Secreted: P48307
Total number of polymer chains4
Total formula weight61453.17
Authors
Schmidt, A.E.,Chand, H.S.,Cascio, D.,Kisiel, W.,Bajaj, S.P. (deposition date: 2005-05-18, release date: 2005-06-07, Last modification date: 2023-08-23)
Primary citationSchmidt, A.E.,Chand, H.S.,Cascio, D.,Kisiel, W.,Bajaj, S.P.
Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition
J.Biol.Chem., 280:27832-27838, 2005
Cited by
PubMed: 15932872
DOI: 10.1074/jbc.M504105200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.802 Å)
Structure validation

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