1ZR0
Crystal Structure of Kunitz Domain 1 of Tissue Factor Pathway Inhibitor-2 with Bovine Trypsin
Summary for 1ZR0
Entry DOI | 10.2210/pdb1zr0/pdb |
Related | 1TAW |
Descriptor | Cationic trypsin, Tissue factor pathway inhibitor 2, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | serine protease; complex of serine protease-inhibitor; kunitz type inhibitor, hydrolase-blood clotting complex, hydrolase/blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00760 Secreted: P48307 |
Total number of polymer chains | 4 |
Total formula weight | 61453.17 |
Authors | Schmidt, A.E.,Chand, H.S.,Cascio, D.,Kisiel, W.,Bajaj, S.P. (deposition date: 2005-05-18, release date: 2005-06-07, Last modification date: 2023-08-23) |
Primary citation | Schmidt, A.E.,Chand, H.S.,Cascio, D.,Kisiel, W.,Bajaj, S.P. Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition J.Biol.Chem., 280:27832-27838, 2005 Cited by PubMed: 15932872DOI: 10.1074/jbc.M504105200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.802 Å) |
Structure validation
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