1ZMD
Crystal Structure of Human dihydrolipoamide dehydrogenase complexed to NADH
Summary for 1ZMD
Entry DOI | 10.2210/pdb1zmd/pdb |
Related | 1ZMC |
Descriptor | Dihydrolipoyl dehydrogenase, SULFATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | e3, lipoamide dehydrogenase, pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, branched-chain alpha-ketoacid dehydrogenase, glycine decarboxylase, glycine cleavage, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P09622 |
Total number of polymer chains | 8 |
Total formula weight | 416253.13 |
Authors | Brautigam, C.A.,Chuang, J.L.,Tomchick, D.R.,Machius, M.,Chuang, D.T. (deposition date: 2005-05-10, release date: 2005-06-28, Last modification date: 2023-08-23) |
Primary citation | Brautigam, C.A.,Chuang, J.L.,Tomchick, D.R.,Machius, M.,Chuang, D.T. Crystal Structure of Human Dihydrolipoamide Dehydrogenase: NAD+/NADH Binding and the Structural Basis of Disease-causing Mutations J.Mol.Biol., 350:543-552, 2005 Cited by PubMed: 15946682DOI: 10.1016/j.jmb.2005.05.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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