1ZKK

Crystal structure of hSET8 in ternary complex with H4 peptide (16-24) and AdoHcy

Summary for 1ZKK

• Entry DOI: 10.2210/pdb1zkk/pdb
• Descriptor: Histone-lysine N-methyltransferase, H4 lysine-20 specific, Peptide corresponding to residues 15-24 of histone H4, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: pseudo-knot, histone h4, beta-sheet, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9NQR1
• Total number of polymer chains: 8
• Total formula weight: 82185.21

Authors

Couture, J.-F.,Collazo, E.,Brunzelle, J.S.,Trievel, R.C. (deposition date: 2005-05-03, release date: 2005-06-07, Last modification date: 2024-02-14)

• Primary citation: Couture, J.-F.,Collazo, E.,Brunzelle, J.S.,Trievel, R.C.; Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase; Genes Dev., 19:1455-1465, 2005; PubMed: 15933070; DOI: 10.1101/gad.1318405

Experimental method

X-RAY DIFFRACTION (1.45 Å)