1ZJ2

Crystal Structure of Human Galactosyltransferase (GTB) Complexed with H type I Trisaccharide

Summary for 1ZJ2

• Entry DOI: 10.2210/pdb1zj2/pdb
• Related: 1ZHJ 1ZI1 1ZI3 1ZI4 1ZI5 1ZIZ 1ZJ0 1ZJ1 1ZJ3 1ZJO 1ZJP
• Related PRD ID: PRD_900049
• Descriptor: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: gtb, abo(h), h-antigen, blood group, transferase, retaining
• Biological source: Homo sapiens (human)
• Cellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• Total number of polymer chains: 1
• Total formula weight: 36384.03

Authors

Letts, J.A.,Rose, N.L.,Fang, Y.R.,Barry, C.H.,Borisova, S.N.,Seto, N.O.,Palcic, M.M.,Evans, S.V. (deposition date: 2005-04-27, release date: 2005-12-13, Last modification date: 2023-08-23)

• Primary citation: Letts, J.A.,Rose, N.L.,Fang, Y.R.,Barry, C.H.,Borisova, S.N.,Seto, N.O.,Palcic, M.M.,Evans, S.V.; Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.; J.Biol.Chem., 281:3625-3632, 2006; PubMed: 16326711; DOI: 10.1074/jbc.M507620200

Experimental method

X-RAY DIFFRACTION (1.69 Å)