1ZHL

Crystal structure of HLA-B*3508 presenting 13-mer EBV antigen LPEPLPQGQLTAY

Summary for 1ZHL

• Entry DOI: 10.2210/pdb1zhl/pdb
• Related: 1ZHK
• Descriptor: HLA class I histocompatibility antigen, B-35 alpha chain, Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, ... (4 entities in total)
• Functional Keywords: t-cell receptor, bulged epitopes, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P30685; Secreted: P61769
• Total number of polymer chains: 3
• Total formula weight: 45159.05

Authors

Tynan, F.E.,Borg, N.A.,Miles, J.J.,Beddoe, T.,El-Hassen, D.,Silins, S.L.,van Zuylen, W.J.,Purcell, A.W.,Kjer-Nielsen, L.,McCluskey, J.,Burrows, S.R.,Rossjohn, J. (deposition date: 2005-04-26, release date: 2005-05-17, Last modification date: 2014-04-16)

• Primary citation: Tynan, F.E.,Borg, N.A.,Miles, J.J.,Beddoe, T.,El-Hassen, D.,Silins, S.L.,van Zuylen, W.J.,Purcell, A.W.,Kjer-Nielsen, L.,McCluskey, J.,Burrows, S.R.,Rossjohn, J.; The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance; J.Biol.Chem., 280:23900-23909, 2005; PubMed: 15849183; DOI: 10.1074/jbc.M503060200

Experimental method

X-RAY DIFFRACTION (1.5 Å)