1Z9H

Microsomal prostaglandin E synthase type-2

Summary for 1Z9H

Entry DOI	10.2210/pdb1z9h/pdb
Descriptor	membrane-associated prostaglandin E synthase-2, ACETATE ION, INDOMETHACIN, ... (5 entities in total)
Functional Keywords	membran associated protein, prostaglandin e synthase, indomethacin, isomerase
Biological source	Macaca fascicularis (crab-eating macaque)
Cellular location	Golgi apparatus membrane ; Single-pass membrane protein . Prostaglandin E synthase 2 truncated form: Cytoplasm, perinuclear region : Q9N0A4
Total number of polymer chains	4
Total formula weight	134408.38
Authors	Yamada, T.,Komoto, J.,Watanabe, K.,Ohmiya, Y.,Takusagawa, F. (deposition date: 2005-04-02, release date: 2005-05-17, Last modification date: 2024-02-14)
Primary citation	Yamada, T.,Komoto, J.,Watanabe, K.,Ohmiya, Y.,Takusagawa, F. Crystal Structure and Possible Catalytic Mechanism of Microsomal Prostaglandin E Synthase Type 2 (mPGES-2). J.Mol.Biol., 348:1163-1176, 2005 Cited by PubMed: 15854652 DOI: 10.1016/j.jmb.2005.03.035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation