1Z7J

Human transthyretin (also called prealbumin) complex with 3, 3',5,5'-tetraiodothyroacetic acid (t4ac)

Replaces:  1KED

Summary for 1Z7J

• Entry DOI: 10.2210/pdb1z7j/pdb
• Related: 1PAB 2ROX
• Descriptor: Transthyretin, 3,3',5,5'-TETRAIODOTHYROACETIC ACID (3 entities in total)
• Functional Keywords: albumin, transport, retinol-binding, vitamin a, amyloid, thyroid hormone, liver, plasma, cerebrospinal fluid, polyneuropathy, disease mutation, tetraiodothyroacetic acid, t4ac, prealbumin, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 2
• Total formula weight: 29050.38

Authors

Neumann, P.,Wojtczak, A.,Cody, V. (deposition date: 2005-03-25, release date: 2005-06-07, Last modification date: 2023-08-23)

• Primary citation: Neumann, P.,Cody, V.,Wojtczak, A.; Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution.; Acta Crystallogr.,Sect.D, 61:1313-1319, 2005; PubMed: 16204882; DOI: 10.1107/S0907444905022523

Experimental method

X-RAY DIFFRACTION (2.2 Å)