1Z3J

Solution Structure of MMP12 in the presence of N-isobutyl-N-4-methoxyphenylsulfonyl]glycyl hydroxamic acid (NNGH)

Summary for 1Z3J

• Entry DOI: 10.2210/pdb1z3j/pdb
• Related: 1YCM
• NMR Information: BMRB: 6444
• Descriptor: Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: macrophage metalloelastase, mmp-12, solution structure, nngh, zinc, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix (Probable): P39900
• Total number of polymer chains: 1
• Total formula weight: 18183.09

Authors

Bertini, I.,Calderone, V.,Cosenza, M.,Fragai, M.,Lee, Y.M.,Luchinat, C.,Mangani, S.,Terni, B.,Turano, P. (deposition date: 2005-03-13, release date: 2005-04-19, Last modification date: 2021-10-20)

• Primary citation: Bertini, I.,Calderone, V.,Cosenza, M.,Fragai, M.,Lee, Y.M.,Luchinat, C.,Mangani, S.,Terni, B.,Turano, P.; Conformational variability of matrix metalloproteinases: Beyond a single 3D structure.; Proc.Natl.Acad.Sci.Usa, 102:5334-5339, 2005; PubMed: 15809432; DOI: 10.1073/pnas.0407106102

Experimental method

SOLUTION NMR