1YP0

Structure of the steroidogenic factor-1 ligand binding domain bound to phospholipid and a SHP peptide motif

Summary for 1YP0

• Entry DOI: 10.2210/pdb1yp0/pdb
• Descriptor: nuclear receptor subfamily 5, group A, member 1, Nuclear receptor subfamily 0, group B, member 2, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... (4 entities in total)
• Functional Keywords: ligand dependent nuclear receptor, steroidogenic factor-1, nr5a1, helical sandwich fold, lbd fold, transcription
• Biological source: Mus musculus (house mouse); More
• Cellular location: Nucleus: P33242; Cytoplasm : P97947
• Total number of polymer chains: 2
• Total formula weight: 29517.50

Authors

Li, Y.,Choi, M.,Cavey, G.,Daugherty, J.,Suino, K.,Kovach, A.,Bingham, N.,Kliewer, S.,Xu, H. (deposition date: 2005-01-28, release date: 2005-04-19, Last modification date: 2024-02-14)

• Primary citation: Li, Y.,Choi, M.,Cavey, G.,Daugherty, J.,Suino, K.,Kovach, A.,Bingham, N.,Kliewer, S.,Xu, H.; Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1.; Mol.Cell, 17:491-502, 2005; PubMed: 15721253; DOI: 10.1016/j.molcel.2005.02.002

Experimental method

X-RAY DIFFRACTION (1.5 Å)