1YI2

Crystal Structure Of Erythromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui

Summary for 1YI2

Entry DOI	10.2210/pdb1yi2/pdb
Descriptor	23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ... (38 entities in total)
Functional Keywords	erythromycin, antibiotic complexes, mutated 50s subunits, ribosome
Biological source	Haloarcula marismortui More
Total number of polymer chains	31
Total formula weight	1481278.23
Authors	Tu, D.,Blaha, G.,Moore, P.B.,Steitz, T.A. (deposition date: 2005-01-11, release date: 2005-04-26, Last modification date: 2024-02-14)
Primary citation	Tu, D.,Blaha, G.,Moore, P.B.,Steitz, T.A. Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Cell(Cambridge,Mass.), 121:257-270, 2005 Cited by PubMed: 15851032 DOI: 10.1016/j.cell.2005.02.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation