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1YHQ

Crystal Structure Of Azithromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui

Summary for 1YHQ
Entry DOI10.2210/pdb1yhq/pdb
Related1YI2 1YIJ
Descriptor23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ... (39 entities in total)
Functional Keywordsazithromycin, antibiotic complexes, mutated 50s subunits, ribosome
Biological sourceHaloarcula marismortui
More
Total number of polymer chains31
Total formula weight1489813.15
Authors
Tu, D.,Blaha, G.,Moore, P.B.,Steitz, T.A. (deposition date: 2005-01-10, release date: 2005-04-26, Last modification date: 2024-02-14)
Primary citationTu, D.,Blaha, G.,Moore, P.B.,Steitz, T.A.
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121:257-270, 2005
Cited by
PubMed: 15851032
DOI: 10.1016/j.cell.2005.02.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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