1YGU
Crystal structure of the tandem phosphatase domains of RPTP CD45 with a pTyr peptide
Summary for 1YGU
| Entry DOI | 10.2210/pdb1ygu/pdb |
| Related | 1YGR |
| Descriptor | Leukocyte common antigen, Polyoma Middle T antigen (2 entities in total) |
| Functional Keywords | cd45, protein tyrosine phosphatase, phosphotyrosine, polyoma middle t antigen, rptp, hydrolase |
| Biological source | Homo sapiens (human) More |
| Cellular location | Membrane; Single-pass type I membrane protein: P08575 Host membrane; Single-pass membrane protein (Potential): P03077 |
| Total number of polymer chains | 4 |
| Total formula weight | 144094.18 |
| Authors | Nam, H.,Poy, F.,Saito, H.,Frederick, C.A. (deposition date: 2005-01-05, release date: 2005-02-22, Last modification date: 2024-04-03) |
| Primary citation | Nam, H.J.,Poy, F.,Saito, H.,Frederick, C.A. Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45. J.Exp.Med., 201:441-452, 2005 Cited by PubMed: 15684325DOI: 10.1084/jem.20041890 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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