1YDN

Crystal Structure of the HMG-CoA Lyase from Brucella melitensis, Northeast Structural Genomics Target LR35.

Summary for 1YDN

Entry DOI	10.2210/pdb1ydn/pdb
Related	1YDO
Descriptor	HYDROXYMETHYLGLUTARYL-COA LYASE, CALCIUM ION (3 entities in total)
Functional Keywords	tim-barrel protein, structural genomics, psi, protein structure initiative, northeast structural genomics consortium, nesg, lyase
Biological source	Brucella melitensis
Total number of polymer chains	4
Total formula weight	126711.86
Authors	Forouhar, F.,Abashidze, M.,Hussain, M.,Vorobiev, S.M.,Xiao, R.,Ciano, M.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2004-12-24, release date: 2005-07-05, Last modification date: 2017-10-11)
Primary citation	Forouhar, F.,Hussain, M.,Farid, R.,Benach, J.,Abashidze, M.,Edstrom, W.C.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Fu, Z.,Kim, J.J.,Miziorko, H.M.,Montelione, G.T.,Hunt, J.F. Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds. J.Biol.Chem., 281:7533-7545, 2006 Cited by PubMed: 16330546 DOI: 10.1074/jbc.M507996200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation