1YBG

MurA inhibited by a derivative of 5-sulfonoxy-anthranilic acid

Summary for 1YBG

Entry DOI	10.2210/pdb1ybg/pdb
Related	1EJC 1EJD 1EYN 1NAW 1Q3G 1UAE
Descriptor	UDP-N-acetylglucosamine 1-carboxyvinyltransferase, N-METHYL-N-{2-[(2-NAPHTHYLSULFONYL)AMINO]-5-[(2-NAPHTHYLSULFONYL)OXY]BENZOYL}-L-ASPARTIC ACID (3 entities in total)
Functional Keywords	inside-out alpha-beta barrel, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Enterobacter cloacae
Cellular location	Cytoplasm : P33038
Total number of polymer chains	4
Total formula weight	181968.37
Authors	Eschenburg, S.,Priestman, M.A.,Abdul-Latif, F.A.,Delachaume, C.,Fassy, F.,Schonbrunn, E. (deposition date: 2004-12-20, release date: 2005-02-15, Last modification date: 2023-08-23)
Primary citation	Eschenburg, S.,Priestman, M.A.,Abdul-Latif, F.A.,Delachaume, C.,Fassy, F.,Schonbrunn, E. A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA). J.Biol.Chem., 280:14070-14075, 2005 Cited by PubMed: 15701635 DOI: 10.1074/jbc.M414412200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation