1Y7J

NMR structure family of Human Agouti Signalling Protein (80-132: Q115Y, S124Y)

Summary for 1Y7J

Entry DOI	10.2210/pdb1y7j/pdb
Related	1HYK 1MR0 1Y7K
Descriptor	Agouti Signaling Protein (1 entity in total)
Functional Keywords	melanocortin; inhibitor; cystine knot; gpcr; endogenous antagonist; inverse agonist, signaling protein
Cellular location	Secreted: P42127
Total number of polymer chains	1
Total formula weight	5824.00
Authors	McNulty, J.C.,Jackson, P.J.,Thompson, D.A.,Chai, B.,Gantz, I.,Barsh, G.S.,Dawson, P.E.,Millhauser, G.L. (deposition date: 2004-12-08, release date: 2005-02-15, Last modification date: 2021-10-20)
Primary citation	McNulty, J.C.,Jackson, P.J.,Thompson, D.A.,Chai, B.,Gantz, I.,Barsh, G.S.,Dawson, P.E.,Millhauser, G.L. Structures of the agouti signaling protein. J.Mol.Biol., 346:1059-1070, 2005 Cited by PubMed: 15701517 DOI: 10.1016/j.jmb.2004.12.030 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation