1Y6K

Crystal structure of human IL-10 complexed with the soluble IL-10R1 chain

Summary for 1Y6K

Entry DOI	10.2210/pdb1y6k/pdb
Related	1J7V 1Y6M 1Y6N
Descriptor	Interleukin-10, Interleukin-10 receptor alpha chain (3 entities in total)
Functional Keywords	helix bundle, receptor complex, immune system
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P22301 Membrane; Single-pass type I membrane protein: Q13651
Total number of polymer chains	2
Total formula weight	43179.00
Authors	Yoon, S.I.,Jones, B.C.,Josepson, K.,Logsdon, N.J.,Walter, M.R. (deposition date: 2004-12-06, release date: 2005-12-20, Last modification date: 2023-08-23)
Primary citation	Yoon, S.I.,Jones, B.C.,Logsdon, N.J.,Walter, M.R. Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain. Structure, 13:551-564, 2005 Cited by PubMed: 15837194 DOI: 10.1016/j.str.2005.01.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.52 Å)

Structure validation