1Y5V

tRNA-Guanine Transglycosylase (TGT) in complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Summary for 1Y5V

Entry DOI	10.2210/pdb1y5v/pdb
Related	1Q4W 1Q63 1Q65 1Q66 1R5Y 1S38 1Y5W 1Y5X
Descriptor	Queuine tRNA-ribosyltransferase, ZINC ION, 6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ... (5 entities in total)
Functional Keywords	transferase
Biological source	Zymomonas mobilis
Total number of polymer chains	1
Total formula weight	43349.44
Authors	Stengl, B.,Meyer, E.A.,Heine, A.,Brenk, R.,Diederich, F.,Klebe, G. (deposition date: 2004-12-03, release date: 2005-12-13, Last modification date: 2023-10-25)
Primary citation	Stengl, B.,Meyer, E.A.,Heine, A.,Brenk, R.,Diederich, F.,Klebe, G. Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding J.Mol.Biol., 370:492-511, 2007 Cited by PubMed: 17524419 DOI: 10.1016/j.jmb.2007.04.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation