1XUF

TRYPSIN-BABIM-ZN+2, PH 8.2

Summary for 1XUF

Entry DOI	10.2210/pdb1xuf/pdb
Descriptor	TRYPSIN, CALCIUM ION, BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE ZINC, ... (4 entities in total)
Functional Keywords	complex, trypsin-zn+2-small molecule ligand, designed small molecule ligand with nanomolar affinity, serine protease
Biological source	Bos taurus (cattle)
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	1
Total formula weight	23762.14
Authors	Katz, B.A.,Clark, J.M.,Finer-Moore, J.S.,Jenkins, T.E.,Johnson, C.R.,Rose, M.J.,Luong, C.,Moore, W.R.,Stroud, R.M. (deposition date: 1997-10-10, release date: 1998-12-16, Last modification date: 2011-07-13)
Primary citation	Katz, B.A.,Clark, J.M.,Finer-Moore, J.S.,Jenkins, T.E.,Johnson, C.R.,Ross, M.J.,Luong, C.,Moore, W.R.,Stroud, R.M. Design of potent selective zinc-mediated serine protease inhibitors. Nature, 391:608-612, 1998 Cited by PubMed: 9468142 DOI: 10.1038/35422 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation