1XQ3

Crystal structure of the human androgen receptor ligand binding domain bound with R1881

Summary for 1XQ3

Entry DOI	10.2210/pdb1xq3/pdb
Related	1E3G 1I37 1XOW 1XQ2
Descriptor	androgen receptor, (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE (3 entities in total)
Functional Keywords	crystal structure; human androgen receptor ligand binding domain; r1881, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P10275
Total number of polymer chains	1
Total formula weight	29330.47
Authors	He, B.,Gampe Jr., R.T.,Kole, A.J.,Hnat, A.T.,Stanley, T.B.,An, G.,Stewart, E.L.,Kalman, R.I.,Minges, J.T.,Wilson, E.M. (deposition date: 2004-10-11, release date: 2004-11-16, Last modification date: 2023-08-23)
Primary citation	He, B.,Gampe Jr., R.T.,Kole, A.J.,Hnat, A.T.,Stanley, T.B.,An, G.,Stewart, E.L.,Kalman, R.I.,Minges, J.T.,Wilson, E.M. Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance Mol.Cell, 16:425-438, 2004 Cited by PubMed: 15525515 DOI: 10.1016/j.molcel.2004.09.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation