Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1XQ0

Structure of human carbonic anhydrase II with 4-[(3-bromo-4-O-sulfamoylbenzyl)(4-cyanophenyl)amino]-4H-[1,2,4]-triazole

Summary for 1XQ0
Entry DOI10.2210/pdb1xq0/pdb
Related1XPZ
DescriptorCarbonic anhydrase II, ZINC ION, 2-BROMO-4-{[(4-CYANOPHENYL)(4H-1,2,4-TRIAZOL-4-YL)AMINO]METHYL}PHENYL SULFAMATE, ... (4 entities in total)
Functional Keywordscarbonic anhydrase, dual aromatase-steroid sulfatase inhibitor (dasi), anti-cancer drug delivery, lyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P00918
Total number of polymer chains1
Total formula weight29737.96
Authors
Lloyd, M.D.,Thiyagarajan, N.,Ho, Y.T.,Woo, L.W.L.,Sutcliffe, O.B.,Purohit, A.,Reed, M.J.,Acharya, K.R.,Potter, B.V.L. (deposition date: 2004-10-11, release date: 2005-05-17, Last modification date: 2023-10-25)
Primary citationLloyd, M.D.,Thiyagarajan, N.,Ho, Y.T.,Woo, L.W.L.,Sutcliffe, O.B.,Purohit, A.,Reed, M.J.,Acharya, K.R.,Potter, B.V.L.
First Crystal Structures of Human Carbonic Anhydrase II in Complex with Dual Aromatase-Steroid Sulfatase Inhibitors(,)
Biochemistry, 44:6858-6866, 2005
Cited by
PubMed: 15865431
DOI: 10.1021/bi047692e
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.76 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon