1XKT

Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain

Summary for 1XKT

Entry DOI	10.2210/pdb1xkt/pdb
Descriptor	fatty acid synthase (2 entities in total)
Functional Keywords	human fatty acid synthase, thioesterase, specificity, drug target, hydroxylase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P49327
Total number of polymer chains	2
Total formula weight	63564.08
Authors	Chakravarty, B.,Gu, Z.,Chirala, S.S.,Wakil, S.J.,Quiocho, F.A. (deposition date: 2004-09-29, release date: 2004-10-26, Last modification date: 2024-02-14)
Primary citation	Chakravarty, B.,Gu, Z.,Chirala, S.S.,Wakil, S.J.,Quiocho, F.A. Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proc.Natl.Acad.Sci.Usa, 101:15567-15572, 2004 Cited by PubMed: 15507492 DOI: 10.1073/pnas.0406901101 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation